85
Participants
Start Date
May 31, 2007
Primary Completion Date
October 31, 2010
Study Completion Date
October 31, 2010
methotrexate
Methotrexate 0.5 mg/kg given by sub cutaneous injection once per week, plus placebo etanercept and and placebo prednisolone
methotrexate - etanercept - prednisolone arm
methotrexate 0.5 mg/kg given by sub cutaneous injection once per week, plus etanercept 0.8 mg/kg given by sub cutaneous injection once per week, plus prednisolone, by mouth daily with decreasing dose tapered over 16 weeks.
Children's Hospital at Montefiore, The Bronx
Schneider Children's Hospital, New Hyde Park
Duke University, Durham
Children's Hospital of Columbus, Columbus
Cleveland Clinic Foundation, Cleveland
Oklahoma University Health Science Center, Oklahoma City
Texas Scottish Rite Hospital, Dallas
University of Utah, Salt Lake City
University of California San Francisco Medical Center, San Francisco
Stanford University Medical Center, Palo Alto
Seattle Children's Hospital and Regional Medical Center, Seattle
Rady Children's Hospital, San Diego
Children's Hospital of Boston, Boston
Hackensack University Medical Center, Hackensack
Cincinnati Children's Hospital Medical Center, Cincinnati
Collaborators (1)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Amgen
INDUSTRY
Seattle Children's Hospital
OTHER