Head to Head Study Against Sevelamer Hydrochloride

PHASE3CompletedINTERVENTIONAL
Enrollment

182

Participants

Timeline

Start Date

January 5, 2007

Primary Completion Date

July 31, 2008

Study Completion Date

July 31, 2008

Conditions
Chronic Kidney Disease, Stage 5
Interventions
DRUG

Fosrenol (Lanthanum Carbonate)

The starting dose is a total daily dose of 2250mg of Fosrenol (Lanthanum carbonate) to a maximum dose of 3000mg daily. Chewable tablets will be administered orally with meals in 750mg and 1000mg strength tablets.

DRUG

Sevelamer hydrochloride

The starting dose is a total daily dose of 4800mg of sevelamer hydrochloride up to a maximum of 6400 mg daily. Sevelamer hydrochloride 800mg tablets, administered orally with meals.

Trial Locations (44)

10559

KfH Nierenzentrum, Berlin

11501

Winthrop Dialysis Center, Mineola

11794

SUNY at Stony Brook NY, Stony Brook

12045

KfH Dialysezentrum/Berlin, Berlin

22030

Clinical Research & Consulting Center, LLC, Fairfax

22297

Dialysezentrum Barmbeck, Hamburg

22304

Alexandria Kidney, Alexandria

27609

Wake Nephrology Associates, Raleigh

28401

Southeastern Nephrology Associates, Wilmington

29605

Carolina Nephrology, PA, Greenville

30901

Kidney Care Associates, LLC, Augusta

31217

Renal Physicians of Georgia, Macon

32608

Shands University of Florida Outpatient Dialysis, Gainesville

33028

Pines Clinical Research, Pembroke Pines

34471

Discovery Medical Research Group, Ocala

37075

Georg-August-Universitat Universitatsmedizin Abt. Nephrologie u. Rheumatologie, Göttingen

37212

VA Tennessee Valley Healthcare System, Nashville

46545

Nephrology Inc., Mishawaka

48249

KfH Nierenzentrum/Dulmen, Dülmen

60201

Evanston Northwestern Hospital, Evanston

60805

Research by Design, LLC, Evergreen Park

64732

KfH Nierenzentrum/Bad/Konig, Bad König

68131

Creighton University Medical Center, Omaha

70809

Renal Associates of Baton Rouge, Baton Rouge

72401

Clinical Research Connections, Jonesboro

78205

Rosa Verde Tower, San Antonio

78229

University of Texas Health Science Center at San Antonio Medicine/Nephrology, San Antonio

80260

Western Nephrology & Metabolic Bone Disease, PC, Thornton

83022

KfH-Dialysezentrum/Rosenheim, Rosenheim

85012

AKDHC Medical Research Services, LLC, Phoenix

85202

DSI Renal Inc., Mesa

85284

Southwest Kidney Institute, PLC, Tempe

Tempe

85724

University of Arizona Health Service Center, Tucson

90073

VA Greater Los Angeles Health Care System, West LA, Los Angeles

91316

South Valley Dialysis Center, Encino

92505

Apex Research of Riverside, Riverside

95991

North Valley Nephrology, Yuba City

97210

Northwest Renal Clinic, Portland

Unknown

Clinical Research Center of Indian River Medical Center, Vero Beach

07724

Hypertension and Nephrology, Associates, Eatontown

07751

KfH-Nierenzentrum/Jena, Jena

00918

Jose Cangiano, MD, San Juan

OX3 7LJ

Churchill Hospital Oxford Kidney Unit, Oxford

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Shire

INDUSTRY