5
Participants
Start Date
January 31, 2008
Primary Completion Date
May 31, 2009
Study Completion Date
May 31, 2009
sodium phenylbutyrate
500 mg/kg/day, depending upon tolerability subsequent dosages may increase to 675, 900, or 1200 mg/kg/day to identify maximum tolerated dose (MTD) and then an additional 6 participants will enroll at the MTD.
Columbia University, 180 Fort Washington Avenue, 5th Floor, New York
University of Texas Southwestern Medical Center at Dallas, Division of Pediatric Neurology, Children's Medical Center of Dallas, Ambulatory Care Pavilion, 2350 Stemmons Freeway, Suite #5074, Dallas
Stanford University Medical Center, 300 Pasteur Drive, Room A343, Stanford
Children's Hospital, Boston, 300 Longwood Avenue, Fegan 11, Boston
The Children's Hospital of Philadelphia, Clinical Trials Office, A-230, 34th St. and Civic Center Boulevard, Philadelphia
Lead Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Westat
OTHER