A Study to Assess the Safety & Interaction Between GW679769, Dexamethasone, & Ondansetron When Taken by Healthy Adults

PHASE1CompletedINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

February 19, 2007

Primary Completion Date

May 15, 2007

Study Completion Date

May 15, 2007

Conditions
Nausea and Vomiting, Chemotherapy-Induced
Interventions
DRUG

Casopitant (GW679769) Oral Tablets

Casopitant (GW679769) tablets will be available as white, film-coated tablets containing 50 mg of GW679769 as the mesylate salt for oral administration.

DRUG

dexamethasone

Dexamethasone will be available as 4 mg tablets for oral administration and injection for IV administration.

DRUG

ondansetron

Ondansetron for oral use will be available as 8 mg tablets to be taken with 240 milliliters (mL) of water on an empty stomach. For IV use, ondansetron 32 mg will be infused intravenously over a period of 15 minutes.

Trial Locations (1)

14202

GSK Investigational Site, Buffalo

Sponsors

Lead Sponsor

All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY

NCT00437229 - A Study to Assess the Safety & Interaction Between GW679769, Dexamethasone, & Ondansetron When Taken by Healthy Adults | Biotech Hunter | Biotech Hunter