ZD6474, Cetuximab, and Irinotecan in Patients With Metastatic Colorectal Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

February 28, 2007

Primary Completion Date

February 29, 2012

Study Completion Date

August 31, 2012

Conditions
Colorectal Cancer
Interventions
DRUG

ZD6474

Orally on a daily basis

DRUG

Cetuximab

Infusion once weekly

DRUG

Irinotecan

Infusion once the safe dose of ZD6474 and cetuximab is established

Trial Locations (3)

02115

Beth Israel Deaconess Medical Center, Boston

Dana-Farber Cancer Institute, Boston

02215

Massachusetts General Hospital, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Massachusetts General Hospital

OTHER

collaborator

Beth Israel Deaconess Medical Center

OTHER

collaborator

AstraZeneca

INDUSTRY

lead

Dana-Farber Cancer Institute

OTHER