A Study of Carboplatin and Gemcitabine Plus Bevacizumab in Patients With Ovary, Peritoneal, or Fallopian Tube Carcinoma

PHASE3CompletedINTERVENTIONAL
Enrollment

484

Participants

Timeline

Start Date

April 30, 2007

Primary Completion Date

September 30, 2010

Study Completion Date

July 31, 2013

Conditions
Ovarian Cancer
Interventions
DRUG

Carboplatin

Carboplatin was provided as commercially available drug.

DRUG

Gemcitabine

Gemcitabine was provided as commercially available drug.

DRUG

Bevacizumab

Bevacizumab was supplied as a clear to slightly opalescent, sterile liquid in glass vials (400 mg in 8 mL \[25 mg/mL\]) with a vehicle consisting of sodium phosphate, trehalose, polysorbate 20, and Sterile Water for Injection, USP.

DRUG

Placebo

Placebo consisted of the vehicle for bevacizumab without the antibody and contained sodium phosphate, trehalose, polysorbate 20, and Sterile Water for Injection, USP.

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY