255
Participants
Start Date
May 31, 2007
Primary Completion Date
July 31, 2009
Study Completion Date
July 31, 2009
Verteporfin Photodynamic Therapy
After a 10-minute intravenous infusion of verteporfin at a dose of 6 mg/m\^2 body surface area, verteporfin was activated by light application of 50 J/cm\^2 to the study eye, begun 15 minutes after the start of the infusion.
Ranibizumab
Ranibizumab 0.5 mg (0.05 mL of 10 mg/mL solution for injection) administered as an intravitreal injection
Placebo
As a placebo for verteporfin photodynamic therapy (for masking purposes), patients were administered a 10-minute intravenous infusion of 5% dextrose solution, followed by light application of 50 J/cm\^2 to the study eye, begun 15 minutes after the start of infusion.
Novartis Investigative site, Vienna
Novartis Investigative site, Antwerp
Novartis Investigative site, Aalborg
Novartis Investigative site, Créteil
Novartis Investigative site, Regensburg
Novartis Investigative site, Budapest
Novartis Investigative site, Florence
Novartis Investigative site, Rotterdam
Novartis Investigative site, Warsaw
Novartis Investigative site, Madrid
Novartis Investigative site, Geneva
Novartis Investigative site, Manchester
Lead Sponsor
Novartis
INDUSTRY