Vinorelbine and Gemcitabine Versus Capecitabine in Pretreated Metastatic Breast Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

144

Participants

Timeline

Start Date

April 30, 2002

Primary Completion Date

January 31, 2009

Study Completion Date

January 31, 2009

Conditions
Breast Cancer
Interventions
DRUG

Gemcitabine

Gemcitabine at the dose of 1000 mg/m2 intravenously (IV) every 2 weeks for 12 consecutive cycles

DRUG

Capecitabine

Capecitabine at the dose of 1250 mg/m2 twice daily orally (os), from day 1 to day 14, every 3 weeks for 6 consecutive cycles

DRUG

Vinorelbine

Vinorelbine at the dose of 25 mg/m2 IV on day 1 every 2 weeks for 12 consecutive cycles

Trial Locations (10)

71110

University Hospital of Crete, Heraklion

Unknown

University General Hospital of Alexandroupolis, Dept. of Medical Oncology, Alexandroupoli

"IASO General Hospital of Athens, 1st Dept. of Medical Oncology", Athens

"Laikon General Hospital, Medical Oncology Unit, Propedeutic Dept. of Internal Medicine", Athens

"Marika Iliadis Hospital of Athens, Dept. of Medical Oncology", Athens

401 Military Hospital of Athens, Athens

Air Forces Military Hospital of Athens, Athens

State General Hospital of Larissa, Dept. of Medical Oncology, Larissa

"Metaxa's Anticancer Hospital of Piraeus, 1st Dept. of Medical Oncology", Piraeus

"Theagenion Anticancer Hospital of Thessaloniki, 2nd Dept. of Medical Oncology", Thessaloniki

All Listed Sponsors
collaborator

University Hospital of Crete

OTHER

lead

Hellenic Oncology Research Group

OTHER