Efficacy and Safety of Oral Febuxostat in Participants With Gout

PHASE3CompletedINTERVENTIONAL
Enrollment

2,269

Participants

Timeline

Start Date

February 28, 2007

Primary Completion Date

March 31, 2008

Study Completion Date

March 31, 2008

Conditions
Gout
Interventions
DRUG

Febuxostat

Febuxostat 40 mg, capsules, orally, once daily for up to 6 months.

DRUG

Febuxostat

Febuxostat 80 mg, capsules, orally, once daily for up to 6 months.

DRUG

Allopurinol

"Allopurinol 200 mg or 300 mg, capsules, orally, once daily for up to 6 months.~Dose is dependent on the subject's renal function. Subjects with normal renal function or mild renal impairment received 300 mg once daily; subjects with moderate renal impairment received 200 mg once daily."

Trial Locations (258)

Unknown

Birmingham

Hoover

Hueytown

Huntsville

Mobile

Montgomery

Northport

Ozark

Tuscaloosa

Chandler

Gilbert

Mesa

Peoria

Phoenix

Scottsdale

Sierra Vista

Tucson

Fort Smith

Jonesboro

Little Rock

Anaheim

Carmichael

Clovis

Concord

El Centro

Fair Oaks

Fullerton

Huntington Beach

Irvine

La Jolla

Laguna Hills

Los Angeles

Pasadena

Rancho Cucamonga

Riverside

Sacramento

San Diego

San Luis Obispo

Santa Barbara

Santa Maria

Torrance

Tustin

Vallejo

Vista

Walnut Creek

West Covina

Westlake Village

Whittier

Boulder

Colorado Springs

Denver

Highlands Ranch

Littleton

Longmont

Wheat Ridge

Danbury

Trumbull

Washington D.C.

Aventura

Boynton Beach

Brandon

Daytona Beach

DeLand

Delray Beach

Fort Lauderdale

Fort Myers

Gainsville

Hallandale

Hialeah

Holly Hill

Jupiter

Kissimmee

Largo

Miami

Naples

New Port Richey

New Smyrna Beach

Opa-locka

Orlando

South Miami

St. Petersburg

Tallahassee

Tampa

West Palm Beach

Winter Haven

Zephyrhills

Atlanta

Conyers

Decatur

Dunwoody

Gainesville

Marietta

Stockbridge

Honolulu

Boise

Coeur d'Alene

Meridian

Nampa

Arlington Heights

Chicago

Evanston

Springfield

Vernon Hills

Elkhart

Evansville

Mishawaka

Clive

Des Moines

Dubuque

Kansas City

Wichita

Elizabethtown

Lexington

Louisville

Baton Rouge

Metairie

New Orleans

Ruston

Shreveport

Slidell

Baltimore

Frederick

Owings Mills

Prince Frederick

Wheaton

Fall River

New Bedford

Springfield

Worcester

Ann Arbor

Flint

Kalamazoo

Lansing

Stevensville

Troy

Chaska

Flowood

Jackson

Olive Branch

Florissant

Jefferson City

Manchester

Mexico

St Louis

Billings

Butte

Grand Island

Lincoln

Omaha

Las Vegas

Reno

Dover

Blackwood

Edison

Flemington

Manalapan

Medford

Midland Park

Albuquerque

Endwell

Mineola

New York

Smithtown

Syracuse

Charlotte

Greensboro

Greenville

Harrisburg

High Point

Lenoir

Raleigh

Winston-Salem

Austintown

Beachwood

Chardon

Cincinnati

Cleveland

Dayton

Hudson

Kettering

Lyndhurst

Perrysburg

Toledo

Willoughby Hills

Youngstown

Oklahoma City

Tulsa

Bend

Eugene

Lake Oswego

Medford

Portland

Bethlehem

Duncansville

East Norriton

Feasterville-Trevose

Harrisburg

Lansdale

Mechanicsburg

Morrisville

Penndel

Philadelphia

Pittsburgh

Reading

Scotland

West Reading

Cranston

East Providence

Charleston

Columbia

Greenville

Greer

Mt. Pleasant

Orangeburg

Simpsonville

Spartanburg

Bristol

Chattanooga

Clarksville

Collierville

Jackson

Johnson City

Memphis

Nashville

New Tazewell

Amarillo

Austin

Beaumont

Bellaire

Bryan

Dallas

El Paso

Fort Worth

Houston

Killeen

Lake Jackson

Odessa

San Antonio

Sugar Land

Waco

Layton

Midvale

Salt Lake City

St. George

West Jordan

Chesapeake

Newport News

Norfolk

Richmond

Everett

Gig Harbor

Lakewood

Olympia

Spokane

Tacoma

Vancouver

Monroe

Oregon

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Takeda

INDUSTRY