Immunotherapy With TG4010 in Patients With Advanced Non-Small Cell Lung Cancer

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

148

Participants

Timeline

Start Date

December 31, 2005

Primary Completion Date

March 31, 2010

Study Completion Date

March 31, 2010

Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL

MVA-MUC1-IL2

"MVA-MUC1-IL2:~Dose of 10exp8 plaque forming units (pfu).~Chemotherapy:~Arm 1 and Arm 2 Intravenous CT: cisplatin (75mg/m² at Day 1) and gemcitabine (1250mg/m² at Days 1 and 8) every 3 weeks, for up to six cycles or until progressive disease, whichever occurred first."

DRUG

1st line Chemotherapy

Trial Locations (23)

8000

Fejér Megyei Szent György Kórház, Székesfehérvár

13273

Institut Paoli-Calmettes, Service d'oncologie médicale, Marseille

14076

Centre François Baclesse, Caen

25000

CHU, Service de Pneumologie, Besançon

35033

CHRU Hôpital de Pontchaillou, Rennes

51109

Lungenklinik Krankenhaus Merheim, Cologne

54151

Centre Hospitalier Général, Service de Pneumologie, Briey

59020

Centre Oscar Lambret, Lille

67100

Hôpital Lyautey - Service de Pneumologie, Strasbourg

68000

Hôpital Pasteur - Service de médecine F- Pavillon 43, Colmar

68167

Klinikum Mannheim der Ruprecht-Karls, Mannheim

69126

Thoraxklinik Heidelberg, Heidelberg

69495

Centre Hospitalier Lyon Sud, Pierre-Bénite

70014

Centre Hospitalier de la Haute Saône, Service de Pneumologie - Allergologie, Vesoul

77654

Klinikum Offenburg, Medizinische Klinik II, Offenburg

82131

Asklepios Fachkliniken, Zentrum für Pneumonologie, Gauting

90016

Centre Hospitalier Belfort-Montbeliard, Belfort

15-540

Oddział II Chorób Płuc i Gruźlicy, Bialystok

85-326

Kujawsko-Pomorskie Centrum Pulmonologii, Bydgoszcz

31-826

Oddział Chemioterapii, Krakow

05-400

Oddział III Chorób Płuc i Gruźlicy, Otwock

60-569

Oddział Onkologii Klinicznej, Poznan

53-439

Dolnośląskie Centrum, Wroclaw

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Transgene

INDUSTRY