NCT00411138 - Randomized Trial of Radiation Therapy With or Without Chemotherapy for Endometrial Cancer | Biotech Hunter

Enrollment

670

Participants

Timeline

Start Date

November 23, 2006

Primary Completion Date

November 29, 2018

Study Completion Date

December 31, 2024

Conditions

Endometrial Cancer

Interventions

RADIATION

Radiation Therapy

External beam pelvic radiotherapy (48.6 Gy in 1.8 Gy fractions) Vaginal brachytherapy boost in case of cervical involvement

DRUG

cisplatin

cisplatin 50 mg/m2 i.v., 2 cycles during radiotherapy, 3 wks interval

DRUG

carboplatin

carboplatin AUC 5, 4 cycles after completion of radiotherapy, 3 wks interval

DRUG

Paclitaxel

paclitaxel 175 mg/m2, 4 cycles after completion of radiotherapy, 3 wks interval

Trial Locations (1)

Leiden University Medical Center, Leiden