Cisplatin, Pemetrexed, and Imatinib Mesylate in Malignant Mesothelioma

PHASE1CompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

August 31, 2006

Primary Completion Date

February 28, 2014

Study Completion Date

February 28, 2014

Conditions
Mesothelioma
Interventions
DRUG

Cisplatin

Starting Dose: 60 mg/m\^2 by vein, Over 2 Hours

DRUG

Imatinib Mesylate

Starting Dose: 300 mg PO Daily

DRUG

Pemetrexed

Starting Dose: 500 mg/m\^2 by vein, Over 40 Minutes

DRUG

Dexamethasone

20 mg by vein given prior to Pemetrexed therapy and 4 mg given orally on Day 2 of each cycle.

Trial Locations (1)

77030

University of Texas MD Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER