A Study of CNTO 328 in Patients With Metastatic Hormone-Refractory Prostate Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 30, 2005

Primary Completion Date

November 30, 2009

Study Completion Date

November 30, 2009

Conditions
Prostatic Neoplasms
Interventions
DRUG

CNTO 328

Patients will receive 6 mg/kg CNTO 328 in treatment phase of cohort 1A and cohort 1B; 9 mg/kg CNTO 328 in treatment phase of cohort 2; and 12 mg/kg CNTO 328 in treatment phase of cohort 3.

DRUG

Docetaxel

Patients will receive 75 mg/m2 docetaxel in run-in phase of cohort 1A, cohort 2, and cohort 3; and in treatment phase of cohort 1A, cohort 1B, cohort 2, and cohort 3.

Trial Locations (5)

Unknown

Baltimore

New York

Chapel Hill

Philadelphia

Nashville

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Centocor, Inc.

INDUSTRY