Study of AT-101 in Combination With Topotecan in Relapsed/Refractory Small Cell Lung Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

November 30, 2006

Primary Completion Date

December 31, 2008

Study Completion Date

December 31, 2008

Conditions
Small Cell Lung Cancer
Interventions
DRUG

AT-101

40 mg of AT-101 (by mouth) on days 1-5 of each 21 day cycle with topotecan 1.25 mg/m2, IV (in the vein) on days 1-5 of each 21 day cycle for approx. 4 cycles or until progression or unacceptable toxicity develops.

DRUG

topotecan

40 mg of AT-101 (by mouth) on days 1-5 of each 21 day cycle with topotecan 1.25 mg/m2, IV (in the vein) on days 1-5 of each 21 day cycle for approx. 4 cycles or until progression or unacceptable toxicity develops.

Trial Locations (19)

35233

Birmingham

55905

Rochester

78705

Austin

92354

Loma Linda

97213

Portland

Unknown

Hot Springs

Stamford

Jacksonville

Lake City

Lebanon

High Point

Columbia

Hilton Head Island

Germantown

Huntington

Research Center (16), Russia

Research Centers (8), Ukraine

02114

Boston

05405

Burlington

Sponsors
All Listed Sponsors
lead

Ascenta Therapeutics

INDUSTRY

NCT00397293 - Study of AT-101 in Combination With Topotecan in Relapsed/Refractory Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter