197
Participants
Start Date
August 1, 2006
Primary Completion Date
March 1, 2007
Study Completion Date
February 1, 2008
Adriamycin and Cytoxan (AC)
Adriamycin (doxorubicin) and Cytoxan (cyclophosphamide) make up the chemotherapy regimen known as AC. Adriamycin 60 mg/m\^2 intravenous, plus Cytoxan 600 mg/m\^2 intravenous on Day 1 of each of four 2-week cycles (weeks 1-8).
ABI-007
260 mg/m\^2 IV on day 1 of each of four 2-week cycle, representing treatment cycles 5-8 (weeks 9-16)
Taxol
175 mg/m\^2 intravenously (IV) on day 1 of each of four 2-week cycle, representing treatment cycles 5-8 (weeks 9-16)
Bevacizumab
10 mg/kg on day 1 of each of eight 2-week cycles (weeks 9-16), then 15 mg/kg on day 1 of each of ten three-week cycles (weeks 17-46).
pegfilgrastim
6 mg subcutaneous (SC) on day 2 for each of the first four 2-week cycles (weeks 1-8). Pegfilgrastim 6 mg SC was administered on day 2 of cycles 6-8 (weeks 11-16) during taxane treatment only if necessary.
Fairfax
Norfolk
Raleigh
Greenville
Birmingham
Indianapolis
Minneapolis
St Louis
Columbia
Dallas
Dallas
Longview
Tyler
Bedford
Fort Worth
Waco
Houston
McAllen
Fredericksburg
Austin
El Paso
Denver
Sedona
Henderson
Eugene
Vancouver
Torrington
Lead Sponsor
Celgene
INDUSTRY