576
Participants
Start Date
November 30, 2006
Primary Completion Date
April 30, 2009
Study Completion Date
March 31, 2010
adalimumab
Prefilled syringe, 40 mg (loading dose then every other week dosing). 80 mg at Week 0, 40 mg at Week 2, and 40 mg every other week starting at Week 4.
adalimumab
Prefilled syringe, 40 mg (loading dose then every other week dosing). 160 mg at Week 0, 80 mg at Week 2, and 40 mg every other week starting at Week 4.
placebo
Placebo for 40 mg syringe. Matching placebo for loading dose and every other week dosing. Subjects received placebo at Weeks 0, 2, 4, and 6, followed by 160 mg adalimumab at Week 8, 80 mg adalimumab at Week 10, and 40 mg adalimumab eow thereafter (prior to Amendment 3) or 40 mg adalimumab eow starting at Week 8 (after Amendment 3).
Site Ref # / Investigator 4937, Vienna
Site Ref # / Investigator 3831, Vienna
Site Ref # / Investigator 3861, Bonheiden
Site Ref # / Investigator 3859, Liège
Site Ref # / Investigator 6224, Hall in Tirol
Site Ref # / Investigator 4936, Graz
Site Ref # / Investigator 3862, Roeselare
Site Ref # / Investigator 2072, New York
Site Ref # / Investigator 3832, Berlin
Site Ref # / Investigator 3855, Prague
Site Ref # / Investigator 3848, Milan
Site Ref # / Investigator 2078, Chevy Chase
Site Ref # / Investigator 2238, Silver Springs
Site Ref # / Investigator 8502, Lund
Site Ref # / Investigator 3833, Kiel
Site Ref # / Investigator 2232, Raleigh
Site Ref # / Investigator 2241, Charlotte
Site Ref # / Investigator 11801, Wilmington
Site Ref # / Investigator 5393, Atlanta
Site Ref # / Investigator 2231, Atlanta
Site Ref # / Investigator 2240, Gainesville
Site Ref # / Investigator 2230, South Miami
Site Ref # / Investigator 2080, Birmingham
Site Ref # / Investigator 6034, Mobile
Site Ref # / Investigator 2076, Nashville
Site Ref # / Investigator 6090, Germantown
Site Ref # / Investigator 3876, Bologna
Site Ref # / Investigator 8503, Gothenburg
Site Ref # / Investigator 2074, Cincinnati
Site Ref # / Investigator 2077, Milwaukee
Site Ref # / Investigator 3878, Mainz
Site Ref # / Investigator 2246, Rochester
Site Ref # / Investigator 2498, Chicago
Site Ref # / Investigator 3858, Brno
Site Ref # / Investigator 2243, Kansas City
Site Ref # / Investigator 2247, Mexico
Site Ref # / Investigator 2233, Lincoln
Site Ref # / Investigator 5100, Fayetteville
Site Ref # / Investigator 3856, Olomouc
Site Ref # / Investigator 3897, Munich
Site Ref # / Investigator 3845, Palermo
Site Ref # / Investigator 14521, Trenčín
Site Ref # / Investigator 5392, San Diego
Site Ref # / Investigator 5390, Orange
Site Ref # / Investigator 2229, Bellevue
Site Ref # / Investigator 2245, Bridgeport
Site Ref # / Investigator 1971, Boston
Site Ref # / Investigator 2236, Cedar Knolls
Site Ref # / Investigator 2126, Cleveland
Site Ref # / Investigator 3830, Innsbruck
Site Ref # / Investigator 7508, Linz
Site Ref # / Investigator 3829, Salzburg
Site Ref # / Investigator 2224, Calgary
Site Ref # / Investigator 2227, Edmonton
Site Ref # / Investigator 2226, Vancouver
Site Ref # / Investigator 2223, Winnipeg
Site Ref # / Investigator 2138, Toronto
Site Ref # / Investigator 3857, Ostrava
Site Ref # / Investigator 3854, Prague
Site Ref # / Investigator 13983, Essen
Site Ref # / Investigator 3834, Jena
Site Ref # / Investigator 3852, Budapest
Site Ref # / Investigator 3850, Budapest
Site Ref # / Investigator 3849, Győr
Site Ref # / Investigator 6232, Rome
Site Ref # / Investigator 3846, Rome
Site Ref # / Investigator 3873, Eindhoven
Site Ref # / Investigator 3875, Leiden
Site Ref # / Investigator 8061, Lodz
Site Ref # / Investigator 13804, Sopot
Site Ref # / Investigator 8055, Warsaw
Site Ref # / Investigator 2392, Ponce
Site Ref # / Investigator 2393, San Juan
Site Ref # / Investigator 3839, Banská Bystrica
Site Ref # / Investigator 3838, Bratislava
Site Ref # / Investigator 3841, Bratislava
Site Ref # / Investigator 3842, Nitra
Site Ref # / Investigator 14721, Prešov
Site Ref # / Investigator 3840, Trnava
Site Ref # / Investigator 8504, Linköping
Lead Sponsor
Abbott
INDUSTRY