Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition.

cangrelor bolus (30 mcg/kg) \& cangrelor infusion (4 mcg/kg/min) administered from randomization for at least 2 hours, or until the end of the PCI, whichever is longer with the option to extend up to 4 hours maximum (per investigator discretion)

clopidogrel capsules (600 mg) at end of PCI

placebo bolus (30 mcg/kg) \& placebo infusion (4 mcg/kg/min) administered from randomization for at least 2 hours, or until the end of the PCI, whichever is longer with the option to extend up to 4 hours maximum (per investigator discretion)

Placebo capsules given at the end of PCI to mimic 600mg clopidogrel dosing

Placebo capsules given at the end of infusion to mimic 600mg clopidogrel dosing