Prospective Evaluation of Elastic Restraint to LESSen the Effects of Heart Failure (PEERLESS-HF) Trial

PHASE2/PHASE3TerminatedINTERVENTIONAL
Enrollment

220

Participants

Timeline

Start Date

October 31, 2006

Primary Completion Date

May 31, 2011

Study Completion Date

May 31, 2012

Conditions
Heart Failure
Interventions
DEVICE

HeartNet Ventricular Support System

The HeartNet Implant is placed on the epicardial surface of the heart surrounding both the left and right ventricles.

DRUG

Optimal Medical/Device Therapy

Optimal Medical/Device Therapy - For the purpose of the PEERLESS-HF study, optimal medical therapy is defined as the use of ACE inhibitors and Beta blockers in the highest tolerable doses for three months prior to study enrollment, and Optimal device therapy is defined as CRT or CRT-D for at least three months prior to study enrollment, when indicated.

Trial Locations (35)

10467

Montefiore Medical Center, The Bronx

14642

University of Rochester Medical Center, Rochester

15212

Allegheny General Hospital, Pittsburgh

17033

Penn State Milton S. Hershey Medical Center, Hershey

19718

Christiana Care Health System, Newark

21201

University of Maryland, Division of Cardiology, Baltimore

22042

Inova Heart & Vascular Institute/ Fairfax Hospital, Falls Church

30322

Emory University, Atlanta

32610

University of Florida, Gainesville

35294

University of Alabama Birmingham, Birmingham

37205

Tennessee Cardiovascular Research Institute, Nashville

38138

The Stern Cardiovascular Center, Germantown

43210

The Ohio State University Medical Center, Columbus

45219

The Lindner Clinical Trial Center, Cincinnati

46260

St. Vincent Hospital and Health Services, Indianapolis

48201

Wayne State University/ Oakwood Hospital, Detroit

52803

Genesis Medical Center, Davenport

55102

St. Paul Heart Clinic, Saint Paul

55417

Minneapolis VA Medical Center, Minneapolis

60148

Midwest Heart Foundation, Lombard

64111

Mid America Heart Institute, Kansas City

68506

BryanLGH Heart Improvement Program, Lincoln

73120

Oklahoma Heart Hospital, Oklahoma City

80045

University of Colorado Health Sciences Center, Aurora

84107

Intermountain Medical Center, Murray

90033

USC Keck School of Medicine, Los Angeles

94143

University of California, San Francisco, Medical Center, San Francisco

02135

Caritas St. Elizabeth's Medical Center, Boston

07962

Morristown Memorial Hospital, Morristown

T2N 4N1

University of Calgary, Calgary

V6Z 1Y6

St. Paul's Hospital, Vancouver

R2H 2A6

St. Boniface General Hospital, Winnipeg

N6A 5A5

London Health Sciences Centre, London

M5G 2C4

Toronto General Hospital, Toronto

H3A 1A1

McGill University Hospital Centre, Montreal

Sponsors
All Listed Sponsors
lead

Paracor Medical, Inc

INDUSTRY

NCT00382863 - Prospective Evaluation of Elastic Restraint to LESSen the Effects of Heart Failure (PEERLESS-HF) Trial | Biotech Hunter | Biotech Hunter