Dose-Finding Study Of CP-675,206 And SU011248 In Patients With Metastatic Renal Cell Carcinoma

PHASE1CompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

November 30, 2006

Primary Completion Date

May 31, 2010

Study Completion Date

May 31, 2010

Conditions
Carcinoma, Renal Cell
Interventions
DRUG

CP-675,206

CP-675,206 administered intravenously every 3 months. Escalating doses from 6mg/kg to 15mg/kg will be tested.

DRUG

SU011248

SU011248 administered at a dose of 37.5mg/day every day.

DRUG

CP-675,206

CP-675,206 administered intravenously every 3 months. Escalating doses from 6mg/kg to 15mg/kg will be tested.

DRUG

SU011248

SU011248 administered at a dose of 50mg/day for 4 weeks followed by 2 weeks off, repeated every 6 weeks.

Trial Locations (5)

29605

Research Site, Greenville

38120

Research Site, Memphis

44195

Research Site, Cleveland

85258

Research Site, Scottsdale

08903

Research Site, New Brunswick

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY