Study of Apixaban for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery

PHASE3CompletedINTERVENTIONAL
Enrollment

3,608

Participants

Timeline

Start Date

November 30, 2006

Primary Completion Date

May 31, 2008

Study Completion Date

May 31, 2008

Conditions
Deep Vein ThrombosisPulmonary Embolism
Interventions
DRUG

Enoxaparin + Placebo

Syringes + tablets, Subcutaneous + Oral, 30mg, twice daily, 12 day treatment period

DRUG

Apixaban + Placebo

Tablet + Syringes, Oral + subcutaneous, 2.5 mg, twice daily, 12 day treatment period

Trial Locations (107)

1012

Local Institution, Capital Federal

1280

Local Institution, Buenos Aires

1425

Local Institution, Buenos Aires

1426

Local Institution, Capital Federal

2229

Local Institution, Caringbah

2300

Local Institution, Kopenhamn S

2480

Local Institution, Lismore

2605

Local Institution, Garran

2970

Local Institution, Hørsholm

3128

Local Institution, Box Hill

3181

Local Institution, Windsor

4215

Local Institution, Gold Coast

5000

Local Institution, Córdoba

5008

Local Institution, Szolnok

5011

Local Institution, Adelaide

5042

Local Institution, Bedford Park

6000

Local Institution, Kecskemét

6001

Local Institution, Perth

7540

Local Institution, Buenos Aires

8000

Local Institution, Székesfehérvár

13083

Local Institution, Campinas

15276

Local Institution, Bialystok

16059

Local Institution, Bursa

18101

Local Institution, Afula

20006

Anthony S. Unger, Md, Washington D.C.

20954

Local Institution, Lublin

22010

Local Institution, Tijuana

29414

Charleston Orthopaedic Assocs., Charleston

30033

Atlanta Knee And Sports Medicine, Decatur

31000

Local Institution, Chihuahua City

31096

Local Institution, Haifa

32216

Jacksonville Center For Clinical Research, Jacksonville

32763

Mark W. Hollmann, Md, Orange City

32789

Jewett Orthopaedic Clinic, Winter Park

33163

Local Institution, Mersin

33511

Pab Clinical Research, Brandon

33744

Bay Pines Va Medical Center, Bay Pines

35205

Capstone Clinical Trials, Inc, Birmingham

35209

Capstone Clinical Trials, Inc, Birmingham

35406

West Alabama Research, Inc., Tuscaloosa

40509

Bluegrass Orthopaedics/Bmr, Lexington

44280

Local Institution, Guadalajara

44281

Local Institution, Kfar Saba

49100

Local Institution, Petah Tikva

58100

Local Institution, Holon

61030

Local Institution, Trabzon

64000

Local Institution, Monterrey

64460

Local Institution, Monterrey

70300

Local Institution, Ẕerifin

71252

Local Institution, Szczecin

72205

Martin Bowen Hefley Orthopedics, Little Rock

76100

Local Institution, Rehovot

77025

Kelsey Seybold Clinic, Houston

77030

Bone & Joint Clinic Of Houston, Houston

78217

Unlimited Research, San Antonio

79410

Gill Orthopedic Center, Lubbock

Robert R. King, Md, Lubbock

80012

Colorado Orthopedic Consultants, Pc, Aurora

80060

Local Institution, Curitiba

80113

Orhtopaedic Physicians Of Colorado, P.C., Englewood

80210

Colorado Joint Replacement, Denver

80230

Jdpmedical Research, Denver

83702

Americana Orthopedics, Boise

Intermountain Orthopaedics, Boise

84101

Local Institution, Beersheba

89240

Local Institution, Ciudad Madero

90020

Local Institution, Porto Alegre, Rs

90035

Local Institution, Porto Alegre

91002

Local Institution, Lodz

91020

Local Institution, Jalapa

97070

Local Institution, Mérida

97133

Local Institution, Mérida

117333

Local Institution, Moscow

195257

Local Institution, Saint Petersburg

443095

Local Institution, Samara

06106

Orthopedics Assocs Of Hartford, Hartford

C1181

Local Institution, Buenos Aires

NSW 2050

Local Institution, Camperdown

05403

Local Institution, São Paulo

T6G 2R7

Local Institution, Edmonton

L1S 2J5

Local Institution, Ajax

L7R 4B7

Local Institution, Burlington

N1R 7L7

Local Institution, Cambridge

N7L 4T1

Local Institution, Chatham

B2Y 2N6

Local Institution, Dartmouth

N1E 6L9

Local Institution, Guelph

K9V 4M8

Local Institution, Lindsay

L3Y 5G8

Local Institution, Newmarket

L2E 6X2

Local Institution, Niagara Falls

N7T 6H3

Local Institution, Sarnia

M1S 4T7

Local Institution, Scarborough Village

M3C 1W3

Local Institution, Scarborough Village

L2R 7P3

Local Institution, St. Catharines

N5A 2N4

Local Institution, Stratford

N2J 1C4

Local Institution, Waterloo

N8W 1E6

Local Institution, Windsor

C1A 1L2

Local Institution, Charlottetown

H4J 1C5

Local Institution, Montreal

G1L 3L5

Local Institution, Québec

01030

Local Institution, Df

05300

Local Institution, Df

07760

Local Institution, Df

31-826

Local Institution, Krakow

00909

Local Institution, Warsaw

02005

Local Institution, Warsaw

416 85

Local Institution, Gothenburg

01330

Local Institution, Adana

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY