NCT00365326 - Safety and Efficacy of Autologous, Intracoronary Stem Cell Injections in Total Coronary Artery Occlusions | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

June 30, 2007

Study Completion Date

June 30, 2008

Conditions

Coronary Occlusion

Interventions

BIOLOGICAL

Catheter-based intracoronary injection

This Phase I single arm clinical study, was designed to assess the safety and feasibility of a dose escalating intracoronary infusion of autologous bone marrow (BM)-derived CD133+ stem cell therapy to the patients with chronic total occlusion (CTO) and ischemia. Nine patients were received CD133+ cells into epicardial vessels supplying collateral flow to areas of viable ischemic myocardium in the distribution of the CTO.

Trial Locations (1)

44106

Case Western Reserve University, Cleveland