A Study of Dasatinib vs. High-Dose Imatinib (600 mg) in Patients With Chronic Phase Chronic Myeloid Leukemia (CML) Who Failed to Achieve Complete Cytogenetic Response After 3-18 Months of Imatinib Therapy

PHASE3TerminatedINTERVENTIONAL
Enrollment

3

Participants

Timeline

Start Date

April 30, 2007

Primary Completion Date

June 30, 2008

Study Completion Date

June 30, 2008

Conditions
Leukemia
Interventions
DRUG

Dasatinib

Tablets, Oral, Once daily, 5-7 years

DRUG

Imatinib

Tablets, Oral, Once daily, 5-7 years

Trial Locations (45)

10021

New York Presbyterian Hospital, New York

10595

New York Medical College, Valhalla

14263

Local Institution, Buffalo

15232

Local Institution, Pittsburgh

21229

Local Institution, Baltimore

27710

Local Institution, Durham

29150

Santee Hematology/Oncology, Sumter

32207

Local Institution, Jacksonville

32209

Local Institution, Jacksonville

32806

M.D. Anderson Cancer Center Orlando, Orlando

33028

Local Institution, Pembroke Pines

35805

Dr. Marshall Schreeder, Huntsville

41701

Local Institution, Hazard

44195

Local Institution, Cleveland

46202

Local Institution, Indianapolis

48109

Local Institution, Ann Arbor

55905

Local Institution, Rochester

60637

Local Institution, Chicago

63110

Local Institution, St Louis

66160

Local Institution, Kansas City

68114

Local Institution, Omaha

72205

Local Institution, Little Rock

73112

Local Institution, Oklahoma City

74136

Local Institution, Tulsa

75390

Local Institution, Dallas

77030

Local Institution, Houston

80045

Local Institution, Aurora

89135

Local Institution, Las Vegas

90033

Local Institution, Los Angeles

90048

Local Institution, Los Angeles

90095

Local Institution, Los Angeles

90211

Local Institution, Beverly Hills

90277

Local Institution, Redondo Beach

90813

Local Institution, Long Beach

91325

Local Institution, Northridge

91750

Local Institution, La Verne

91801

Local Institution, Alhambra

92093

Local Institution, La Jolla

92801

Local Institution, Anaheim

92835

Local Institution, Fullerton

93030

Local Institution, Oxnard

93454

Local Institution, Santa Maria

94143

Local Institution, San Francisco

94305

Local Institution, Stanford

07601

Local Institution, Hackensack

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT00362466 - A Study of Dasatinib vs. High-Dose Imatinib (600 mg) in Patients With Chronic Phase Chronic Myeloid Leukemia (CML) Who Failed to Achieve Complete Cytogenetic Response After 3-18 Months of Imatinib Therapy | Biotech Hunter | Biotech Hunter