Study to Evaluate Eye Function in Patients Taking Linezolid for Six Weeks or Greater

PHASE3TerminatedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

November 30, 2008

Primary Completion Date

December 31, 2013

Study Completion Date

December 31, 2013

Conditions
Optic Nerve Diseases
Interventions
DRUG

Zyvox - linezolid

Observation and testing in patients for whom their treating physician has determined linezolid is an appropriate therapy. Eye tests performed for subjects who have received linezolid for at least 6 weeks and matching controls who have received other antibiotics for similar types of infections.

DRUG

Matched control

Matched controls received an antibiotic other than linezolid for at least 6 weeks prior to baseline visit. The control group had only a baseline visit and there were no post baseline study visits.

Trial Locations (12)

15206

Associates in Infectious Disease and Tropical Medicine, Pittsburgh

16132

Azienda Ospedaliera Universitaria di San Martino, Genova

Ospedale San Martino, Clinica Malattie Infettive, Genova

Università di Genova, Genova

19102

Drexel University College of Medicine, Partnership Comprehensive Care Practice, Philadelphia

33100

Clinica Malattie Infettive, Azienda Ospedaliero Universitaria Santa Maria della Misericordia, Udine

33401

Triple O Research Institute, PA, West Palm Beach

48202

Henry Ford Health System, Detroit

55455

University of Minnesota, Department of Medicine/Division of Infectious Diseases, Minneapolis

70121

Ochsner Clinic Foundation, New Orleans

72401

St. Bernards Research Center, Jonesboro

141 86

Infektionskliniken 1-73, Karolinska Universitetssjukhuset Huddinge, Stockholm

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY