49
Participants
Start Date
January 31, 2005
Primary Completion Date
March 31, 2011
Study Completion Date
March 31, 2011
5-Fluorouracil
"400 mg/m\^2 injection by vein Day 1 of 14 day cycle immediately after completion of leucovorin infusion.~2.4 g/m\^2 by vein over 46 hours over Days 1-3 of 14 day cycle immediately after completion of 400 mg/m\^2 injection."
Bevacizumab
"5 mg/kg over 90 minutes on Day 1 of first 14 day cycle as initial dose, administered alone without other drugs.~5 mg/kg by vein on Day 1 of 14 day cycle."
Leucovorin
400 mg/m\^2 over 2-4 minutes by vein on Day 1 of 14 day cycle.
Irinotecan
180 mg/m\^2 by vein over 90 minutes on Day 1 of 14 day cycle.
Lyndon Baines Johnson General Hospital, Houston
UT MD Anderson Cancer Center, Houston
Collaborators (2)
Genentech, Inc.
INDUSTRY
Pfizer
INDUSTRY
M.D. Anderson Cancer Center
OTHER