69
Participants
Start Date
September 30, 2005
Primary Completion Date
June 30, 2011
Study Completion Date
June 30, 2011
Cetuximab
500 mg/m\^2 IV/week +/-1 day continued throughout induction chemotherapy, chemoradiation and maintenance chemotherapy.
Gemcitabine
"Induction Therapy: 1 gm/m\^2 over 100 minutes every 2 weeks +/-1 day for 4 doses.~Chemotherapy Maintenance: 1 gm/m\^2/week over 100 minutes weekly for 3 weeks then 1 week off."
Oxaliplatin
Induction Chemotherapy: 100 mg/m\^2 over 120 minutes every 2 weeks +/-1 day for 4 doses.
Capecitabine
Chemoradiation (to start 2-3 weeks post completion of oxaliplatin and gemcitabine): 825 mg/m\^2 by mouth (PO) twice daily Monday-Friday throughout radiation.
Radiotherapy
Conformal radiation therapy to gross disease, total dose = 50.4 Gy delivered in 28 fractions.
UT MD Anderson Cancer Center, Houston
Collaborators (1)
Bristol-Myers Squibb
INDUSTRY
M.D. Anderson Cancer Center
OTHER