NCT00330304View on ClinicalTrials.gov

Isoniazid Prophylaxis With Concomitant Cotrimoxazole in HIV-infected Children

PHASE3CompletedINTERVENTIONAL
Enrollment

450

Participants

Timeline

Start Date

January 31, 2003

Primary Completion Date

November 15, 2011

Study Completion Date

November 15, 2011

Conditions
Tuberculosis
Interventions
DRUG

Isoniazid

isoniazid 10mg/kg orally, daily, for study period

DRUG

Cotrimoxazole

Cotrimoxazole given 3 times a week or daily, orally, for study period

DRUG

isoniazid

Isoniazid, 10mg/kg daily for study period

OTHER

placebo

Placebo tablet identicle in appearance to intervention: isoniazid table

Trial Locations (2)

7700

Red Cross Childrens Hospital, Cape Town

Unknown

Tygerberg Hospital, Cape Town

Sponsors

Collaborators (1)

Medical Research Council
All Listed Sponsors
collaborator

University of Stellenbosch

OTHER

collaborator

Medical Research Council

OTHER_GOV

collaborator

Rockefeller Foundation

OTHER

lead

University of Cape Town

OTHER