The Effects of Eicosapentaenoic Acid (EPA), Gamma-Linolenic Acid (GLA) and Antioxidants in the Treatment of Sepsis

PHASE4CompletedINTERVENTIONAL
Enrollment

115

Participants

Timeline

Start Date

June 30, 2007

Primary Completion Date

December 31, 2008

Study Completion Date

October 31, 2009

Conditions
SepsisSevere SepsisSeptic Shock
Interventions
DIETARY_SUPPLEMENT

Eicosapentaenoic acid, Gamma-Linolenic Acid and Antioxidant Vitamins

An enteral diet will be given in accordance with the caloric goal calculated by the Harris-Benedict equation x 1.3. The enteral diet will be provided for a period of 7 days or until death OR start of oral diet OR start of parenteral diet OR discharge from the ICU OR decision from the attending physician/family/patient to no longer participate in this clinical study

DIETARY_SUPPLEMENT

Standard ICU enteral diet, isocaloric to the study diet

Patients will receive this diet in a blinded way using the same dose regimen specified previously and used in the study group

Trial Locations (12)

21000000

Clínica São Vicente, Rio de Janeiro

Hospital Pró-Cardíaco, Rio de Janeiro

60000000

Hospital de Clínicas da Universidade Federal da Paraíba, João Pessoa

60.115-000

Hospital Fernandes Távora - Adult Intensive Care Unit, Fortaleza

40.130-030

Hospital Português - Real Sociedade Portuguesa 16 de Setembro, Salvador

Hospital Salvador, Salvador

Unknown

Hospital Santa Luzia, Brasília

89.204-050

Associação Beneficente Evangélica de Joinville - Hospital Dona Helena, Joinville

89.204-060

Centro Hospitalar Unimed, Joinville

15.090-000

Fundação Faculdade de Medicina de São José Do Rio Preto, São José do Rio Preto

04.024-900

Hospital São Paulo-UNIFESP, São Paulo

04.039-901

Instituto de Assistência Médica Ao Servidor Público Estadual-Iamspe, São Paulo

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Abbott

INDUSTRY

lead

Fernandes Tavora Hospital

OTHER