A Phase I/II Study of MGCD0103 With Azacitidine in Patients With High-Risk Myelodysplastic Syndrome (MDS) or Acute Myelogenous Leukemia

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

November 30, 2008

Study Completion Date

November 30, 2008

Conditions
Myelodysplastic SyndromeAcute Myelogenous Leukemia
Interventions
DRUG

MGCD0103

MGCD0103 Oral administration 3 times per week.

Trial Locations (8)

10021

Memorial Sloan-Kettering Cancer Center, New York

15224

The Western Pennsylvania Hospital, Pittsburgh

19104

University of Pennsylvania, Philadelphia

19107

Thomas Jefferson University Hospital, Philadelphia

Thomas Jefferson University, Philadelphia

46107

St. Francis Hospital & Health Center, Beech Grove

77030

University of Texas, MD Anderson Cancer Center, Houston

90033

University of Southern California, Los Angeles

Sponsors
All Listed Sponsors
lead

Mirati Therapeutics Inc.

INDUSTRY

NCT00324220 - A Phase I/II Study of MGCD0103 With Azacitidine in Patients With High-Risk Myelodysplastic Syndrome (MDS) or Acute Myelogenous Leukemia | Biotech Hunter | Biotech Hunter