A Phase II Controlled Trial of Velafermin for Prevention of Oral Mucositis

PHASE2CompletedINTERVENTIONAL
Enrollment

390

Participants

Timeline

Start Date

May 31, 2006

Primary Completion Date

August 31, 2008

Study Completion Date

August 31, 2008

Conditions
Oral MucositisStomatitis
Interventions
DRUG

velafermin

administered intravenously as 100mL single dose over 15 minutes on day 1

DRUG

placebo

administered intravenously as 100mL single dose over 15 minutes on day 1

Trial Locations (33)

10021

Cornell Medical Center, New York

10029

Biomedical Research Alliance of New York, New York

10467

Biomedical Research Alliance of New York, The Bronx

19111

Fox Chase-Temple Bone Marrow Transplant Program, Philadelphia

27157

Wake Forest University Health Sciences, Winston-Salem

27599

University of North Carolina, Chapel Hill

27710

Duke University Medical Center, Durham

29425

Medical University of South Carolina Hollings Cancer Center, Charleston

30322

Emory University, Atlanta

44106

University Hospitals of Cleveland, Cleveland

46107

St. Francis Hospital and Health Centers, Beech Grove

46202

Indiana University Cancer Center, Indianapolis

48201

Wayne State University, Detroit

52242

University of Iowa Hospitals and Clinics, Iowa City

53226

Medical College of Wisonsin, Milwaukee

55905

MAYO Clinic, Rochester

60611

Northwestern University, Chicago

60612

Rush University Medical Center, Chicago

66160

University of Kansas Medical Center, Kansas City

71130

Louisiana State University Health Science Center, Shreveport

72205

University of Arkansas for Medical Sciences, Little Rock

73104

University of Oklahoma, Oklahoma City

75246

Baylor University Medical Center, Dallas

80045

University of Colorado Health Sciences Center, Aurora

80218

Rocky Mountain Blood and Marrow Transplant Program, Denver

92037

Research Facility, La Jolla

Scripps Green Medical Center, La Jolla

94704

Alta Bates Comprehensive Cancer Center, Berkley

97227

Legacy Good Samaritan Hospital and Cancer Center, Portland

97239

Oregon Health and Science University, Portland

07601

Cancer Center at Hackensack University Medical Center, Hackensack

02908

Roger Williams Medical Center, Providence

78229-3900

University of Texas Health Science Center, San Antonio

Sponsors
All Listed Sponsors
lead

CuraGen Corporation

INDUSTRY