Effectiveness of MORAb-003 in Women With Ovarian Cancer Who Have Relapsed After Platinum-Based Chemotherapy

PHASE2CompletedINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

May 31, 2006

Primary Completion Date

February 28, 2010

Study Completion Date

June 30, 2010

Conditions
Ovarian CancerFallopian Tube CancerPeritoneal Neoplasms
Interventions
DRUG

Farletuzumab

Weekly Farletuzumab infusions Dose dependent on dosing group

DRUG

Chemo Plus Far

Chemo+Far: paclitaxel 175 mg/m2 (or docetaxel, 75 mg/m2) plus carboplatin area under the concentration-time curve (AUC) 5-6 intravenously (IV) on Day 1 of a 21-day cycle plus farletuzumab, 100 mg/m2.

Trial Locations (20)

12206

New York Oncology Hematology, Albany

18104

Lehigh Valley Women's Cancer Center, Allentown

21231

Johns Hopkins University, Baltimore

22003

Northern Virginia Pelvic Surgery Associates, Annandale

23601

Peninsula Cancer Center, Newport News

29601

Gynecology Oncology Research & Development, Greenville

44718

Gabrail Cancer Center, Canton

46260

St. Vincent Gynecologic Oncology, Indianapolis

70006

Jayne Gurtler, M.D., Metairie

Hematology and Oncology Specialists, LLC, Metarie

70433

Hematology and Oncology Specialists, LLC, Covington

75246

Mary Crowley Medical Research Center, Dallas

75702

Tyler Cancer Center, Tyler

78229

South Texas Oncology & Hematology, San Antonio

92123

Sharp HealthCare, San Diego

08003

The Center for Cancer and Hematologic Disease, Cherry Hill

08901

The Cancer Institute of New Jersey, New Brunswick

08043

Cooper University Hospital, Voorhees Township

Unknown

Krankenhaus Nordwest, Frankfurt

Nationales Centrum fur Tumorerkrankungen, Heidelberg

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Morphotek

INDUSTRY