Study of BMS-477118 as Monotherapy With Titration in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

PHASE3CompletedINTERVENTIONAL
Enrollment

365

Participants

Timeline

Start Date

June 30, 2006

Primary Completion Date

November 30, 2007

Study Completion Date

November 30, 2008

Conditions
Diabetes
Interventions
DRUG

Saxagliptin

Coated tablets, Oral, 2.5 mg, QAM, Daily (6 months ST, 12 months LT)

DRUG

Saxagliptin

Coated tablets, Oral, 2.5 mg titrated to 5mg, QAM, Daily (6 months ST, 12 months LT)

DRUG

Saxagliptin

Coated tablets, Oral, 5mg, QAM, Daily, (6 months ST, 12 months LT)

DRUG

Saxagliptin

Coated tablets, Oral, 5mg QPM, Daily (6 months ST, 12 months LT)

DRUG

Placebo

Coated tablets, Oral, 0mg, Daily (6 months ST, 12 months LT)

DRUG

metformin

Tablets, Oral, 500-2000 mg, as needed (12 months LT)

Trial Locations (74)

114

Local Institution, Taipei

333

Local Institution, Tao-Yuan County

402

Local Institution, Taichung

407

Local Institution, Taichung

500

Local Institution, Changhua

833

Local Institution, Kaohsiung County

12401

Hudson Valley Clinical Research Center, Kingston

15216

Banksville Medical, Pc, Pittsburgh

17015

Cumberland Valley Endocrinology Center, Llc, Carlisle

17257

Biomedical Research Associates, Llc, Shippensburg

19522

Fleetwood Clinical Research, Fleetwood

23451

Tidewater Integrated Medical Research, Virginia Beach

27834

Diabetes Center- East Carolina University, Greenville

28144

Crescent Medical Research, Salisbury

28262

Neem Research Group Of Charlotte, Charlotte

29334

Middle Tyger Family Medicine, Duncan

29687

Southeastern Research Assoc, Taylors

32714

Central Florida Clinical Trials, Inc., Altamonte Springs

32935

Accelovance, Melbourne

33707

Premier Healthcare, St. Petersburg

34243

University Family Healthcare, Pa, Sarasota

35051

Tomac, Inc., Columbiana

35565

Winston Technology, Inc., Haleyville

37660

Holston Medical Group, Kingsport

38017

Collierville Medical Specialist, Collierville

38116

Med-South Research, Memphis

38125

Southwind Medical Specialist, Memphis

38134

Versoza & Ungab Internal Medicine Associates, Bartlett

43551

Clinical Research Source, Inc, Perrysburg

44203

Community Health Care, Inc., Barberton

44718

Clinical Research Limited, Canton

45429

Wells Institute For Health Awareness, Kettering

63385

Primary Care Physicians, Pc, Wentzville

64106

Kansas City University Of Medicine And Biosciences, Kansas City

66215

Pinnacle Medical Research, Overland Park

73112

Accelovance, Oklahoma City

73170

Integris Family Care South, Oklahoma City

75010

Precision Family Medicine, Carrollton

77024

Village Family Practice, Houston

77081

Texas Center For Drug Development, P.A., Houston

78224

Abbott Clinical Research Group, Inc, San Antonio

78411

Alpha Therapy Research Center, Corpus Christi

84010

Taylor/Wade Medical, Bountiful

84102

Optimum Clinical Research, Salt Lake City

85213

Clinical Reseacrh Advantage/ Brown Family Medicine, Mesa

90201

Rx For Life, Inc, Cudahy

90660

In Private Prictice Clinic, Pico Rivera

91325

Diabetes Medical Center Of California, Northridge

91436

Medical Group Of Encino, Encino

91505

Providence Clinical Research, Burbank

92708

Southland Clinical Research Center, Inc., Fountain Valley

93311

Strategos Medical Group, Bakersfield

93720

Valley Research, Fresno

95128

San Jose Clinical Research, Inc., San Jose

97404

The Office Of Patricia Buchanan, Eugene

99216

Spokane Internal Medicine, Spokane

110076

Local Institution, Sarita Vihar

115487

Local Institution, Moscow

118089

Local Institution, Moscov

194156

Local Institution, Saint Petersburg

198013

Local Institution, Saint Petersburg

214018

Local Institution, Smolensk

400007

Local Institution, Mumbai

400021

Local Institution, Mumbai

400138

Local Institution, Volgograd

410018

Local Institution, Saratov

410054

Local Institution, Saratov

440012

Local Institution, Nagpur

560034

Local Institution, Bangalore

575001

Local Institution, Attavar

576104

Local Institution, Manipal

603126

Local Institution, Nizhny Novgorod

682026

Local Institution, Kochi

08755

Physicians Research Center, Toms River

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY