Randomized Study Comparing Pre- and Postoperative vs. Conventional Adjuvant Treatment in Receptor-negative Patients

PHASE3CompletedINTERVENTIONAL

Enrollment

429

Participants

Timeline

Start Date

October 31, 1991

Primary Completion Date

September 30, 2000

Study Completion Date

September 30, 2000

Conditions

Early Stage Breast Cancer

Interventions

DRUG

Cyclophosphamide

Cyclophosphamide 600mg/m2

DRUG

Methotrexate

Methotrexate 40mg/m2

DRUG

Fluorouracil

Fluorouracil 600mg/m2

DRUG

Epirubicin

Epirubucin 60mg/m2 (only node-positive patients)

OTHER

Surgery

All Listed Sponsors

lead

Austrian Breast & Colorectal Cancer Study Group

NETWORK