NCT00309491 - Randomized Study Comparing Tamoxifen vs. Tamoxifen + Aminoglutethimide in Postmenopausal Receptor-positive Patients | Biotech Hunter

Enrollment

2,021

Participants

Timeline

Start Date

December 31, 1990

Primary Completion Date

January 31, 1996

Study Completion Date

March 31, 2000

Conditions

Early-stage Breast Cancer

Interventions

DRUG

Tamoxifen alone

2 x 20 mg tamoxifen daily, start of therapy within 4 weeks after surgery; therapy duration 5 years

DRUG

Tamoxifen + Aminoglutethimide

"2 x 20 mg tamoxifen daily (5 years) plus Aminoglutethimide daily (first 2 years)~* 1st therapy week:125mg/-/125mg Aminoglutethimide daily~* 2nd therapy week: 125mg/-/250mg Aminoglutethimid daily~* as of 3rd therapy week: 250mg/-/250mg Aminoglutethimid daily"