NCT00307736 - Bevacizumab, Erlotinib and 5-Fluorouracil With External Beam Radiation Therapy in Locally Advanced Rectal Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 31, 2006

Primary Completion Date

April 30, 2010

Study Completion Date

July 31, 2011

Conditions

Rectal CancerAdenocarcinoma of the Rectum

Interventions

DRUG

5-fluorouracil

Given as a 24-hour infusion on days 1-14 of each 14-day cycle for a total of 3 cycles.

DRUG

bevacizumab

Given intravenously on day 1 of each 14-day cycle for a total of 3 cycles.

DRUG

erlotinib

Taken orally on days 1-14 of each 14-day cycle for a total of 3 cycles.

PROCEDURE

External beam radiation therapy (EBRT)

Given on days 1-5 and 8-12

Trial Locations (3)

Beth Israel Deaconess Medical Center, Boston

Dana-Farber Cancer Institute, Boston

Massachusetts General Hospital, Boston