HuMax-CD20 in Active Rheumatoid Arthritis, Phase I/II

PHASE2CompletedINTERVENTIONAL
Enrollment

201

Participants

Timeline

Start Date

February 28, 2005

Primary Completion Date

September 30, 2007

Study Completion Date

September 30, 2007

Conditions
Arthritis, Rheumatoid
Interventions
DRUG

Part A

Part A Cohort 1: HuMax-CD20 300 mg at Days 0 and 14 or Placebo at Days 0 and 14 Cohort 2: HuMax-CD20 700 mg at Days 0 and 14 or Placebo at Days 0 and 14 Cohort 3: HuMax-CD20 1000 mg at Days 0 and 14 or Placebo at Days 0 and 14

DRUG

Part B

Part B Group 1: HuMax-CD20 300 mg at Days 0 and 14 Group 2: HuMax-CD20 700 mg at Days 0 and 14 Group 3: HuMax-CD20 1000 mg at Days 0 and 14 Group 4: Placebo at Days 0 and 14

Sponsors

Lead Sponsor

All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY