Study of Ipilimumab (MDX-010) Monotherapy in Patients With Previously Treated Unresectable Stage III or IV Melanoma

PHASE2CompletedINTERVENTIONAL
Enrollment

210

Participants

Timeline

Start Date

April 30, 2006

Primary Completion Date

July 31, 2007

Study Completion Date

July 31, 2007

Conditions
Melanoma
Interventions
DRUG

ipilimumab (MDX-010, BMS-734016)

IV solution, IV, 0.3mg/kg, Q 3 wks for 12 wks then Q 12 wks, 48+ weeks depending on response.

DRUG

Ipilimumab

IV solution, IV, 3 mg/kg, Q 3 wks for 12 wks then Q 12 wks, 48+ weeks depending on response.

DRUG

Ipilimumab

IV solution, IV, 10 mg/kg, Q 3 wks for 12 wks then Q 12 wks, 48+ weeks depending on response.

Trial Locations (62)

1070

Local Institution, Brussels

1090

Local Institution, Brussels

1200

Local Institution, Brussels

2199

Local Institution, Johannesburg

2300

Local Institution, Newcastle

3084

Local Institution, Heidelberg

3690

Local Institution, Wodonga

4101

Local Institution, Brisbane

7506

Local Institution, Cape Town

7624

Local Institution, Pécs

10021

Memorial Sloan Kettering Cancer Center, New York

12200

Local Institution, Berlin

13009

Local Institution, Marseille

17210

Local Institution, Jaú

21237

Harry And Jeanette Weinberg Cancer Inst At Franklin Square, Baltimore

24105

Local Institution, Kiel

28204

Presbyterian Hospital, Charlotte

29200

Local Institution, Brest

29615

Cancer Centers Of The Carolinas, Greenville

31059

Local Institution, Toulouse

32207

Baptist Cancer Institute, Jacksonville

32806

Md Anderson Cancer Center Orlando, Orlando

33140

Mount Sinai Comprehensive Cancer Center, Miami Beach

33401

Palm Beach Cancer Institute, West Palm Beach

35042

Local Institution, Rennes

40202

University Of Louisville, Louisville

44195

Cleveland Clinic, Cleveland

45122

Local Institution, Essen

45219

The Christ Hospital Cancer Center Research, Cincinnati

46202

American Health Network, Indianapolis

54511

Local Institution, Vandœuvre-lès-Nancy

55422

Hubert H. Humphrey Cancer Center, Robbinsdale

60068

Oncology Specialists, Sc, Park Ridge

63058

Local Institution, Clermont-Ferrand

63110

Washington University School Of Medicine, St Louis

64507

St Joseph Oncology Inc, Saint Joseph

65203

Ellis Fischel Cancer Center, Columbia

68169

Local Institution, Mannheim

69115

Local Institution, Heidelberg

69288

Local Institution, Lyon

69373

Local Institution, Lyon

75010

Local Institution, Paris

75230

Center For Oncology Research & Treatment, P.A., Dallas

75246

Mary Crowley Medical Research Center, Dallas

85724

Arizona Cancer Center, Tucson

90020

Local Institution, Centro-Porto Alegre

90404

The Angeles Clinic And Research Institution, Santa Monica

90610

Local Institution, Porto Alegre

91750

Wilshire Oncology Medical Group Inc, Laverne

92121

Scripps Cancer Center, San Diego

97080

Local Institution, Würzburg

97213

Providence Portland Medical Center, Portland

06520

Yale University School Of Medicine, New Haven

01509

Local Institution, São Paulo

T2N 4N2

Local Institution, Calgary

T6G 1Z2

Local Institution, Edmonton

K7L 5P9

Local Institution, Kingston

775 20

Local Institution, Olomouc

128 08

Local Institution, Prague

07740

Local Institution, Jena

0041

Local Institution, Pretoria

0181

Local Institution, Pretoria

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Medarex

INDUSTRY

lead

Bristol-Myers Squibb

INDUSTRY