A Study to Evaluate the Efficacy and Safety of Rituximab in Subjects With International Society of Nephrology/Renal Pathology Society (ISN/RPS) 2003 Class III or IV Lupus Nephritis

PHASE3CompletedINTERVENTIONAL

Enrollment

144

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

January 31, 2009

Study Completion Date

January 31, 2013

Conditions

Lupus Nephritis

Interventions

DRUG

Rituximab

Rituximab was provided as a sterile solution for injection.

DRUG

Placebo

Placebo was provided as a sterile solution for injection.

DRUG

Mycophenolate mofetil

DRUG

Methylprednisolone

DRUG

Diphenhydramine

DRUG

Acetaminophen

DRUG

Prednisone