103
Participants
Start Date
January 23, 2006
Primary Completion Date
January 31, 2008
Study Completion Date
May 28, 2012
Rituximab
Rituximab was supplied in single-use vials.
Methotrexate
Methylprednisone
Patients received methylprednisolone 100 mg intravenously before each infusion of rituximab.
C. albicans
Patients received an intradermal injection of C. albicans (0.1 mL) on the volar surface of the forearm.
Tetanus toxoid adsorbed booster vaccine
Patients received an intramuscular injection of the tetanus toxoid adsorbed booster vaccine (1 mg in 0.5 mL) in the deltoid muscle.
23-valent pneumococcal polysaccharide vaccine
Patients received an intramuscular injection of the 23-valent pneumococcal polysaccharide vaccine (0.5 mL) in the deltoid muscle.
Keyhole limpet hemocyanin
Patients received a subcutaneous injection of keyhole limpet hemocyanin (1 mg)
Center for Rheumatology, State Uni. of New York, Albany
Aair Research Center, Rochester
University of Rochester - Strong Memorial Hospital, Rochester
Altoona Arthritis & Osteo Center, Duncansville
University of Pennsylvania, Philadelphia
Johns Hopkins University; Rheumatology, Baltimore
Arthritis Clinic of Northern Virginia, Arlington
Physicians East Pa, Greenville
Rheumatology Associates, Charleston
Medical University of S. Carolina, Charleston
Center For Arthritis; Research Dept, South Miami
Arthritis Associates of South Florida, Delray Beach
The Arthritis Center, Palm Harbor
Univ of Alabama at Birmingham, Birmingham
Arthritis Associates, Hixson
Kentuckiana Center For Better Bone & Joint Healthx, Louisville
Justus Fiechtner MD - PP, Lansing
Rheumatology, P.C.; Medical Arts Building, Kalamazoo
Borgess Research Institute, Kalamazoo
Northwestern University, Chicago
Univ of Chicago, Chicago
Springfield Clinic, Springfield
Clinical Research Network, Slidell
Health Research of Oklahoma, Llc, Oklahoma City
Intermountain Orthopaedics, Boise
Arizona Arthritis & Rheumatology Research, Pllc, Paradise Valley
Sun Valley Arthritis Center, Peoria
Inland Rheumatology; Clinical Trials, Inc., Upland
Desert Medical Advances, Palm Desert
Oregon Health Sciences Uni, Portland
Arthritis Northwest, Spokane, Spokane
Evanston Northwestern Healthcare, Evanston
Dana Farber Cancer Institute, Boston
Arthritis Care & Diagnostic Center, Dallas
Lead Sponsor
Genentech, Inc.
INDUSTRY