NCT00280787 - Induction Chemotherapy Using Paclitaxel, Carboplatin, CPT-11 With Pegfilgrastim | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 30, 2003

Primary Completion Date

January 31, 2006

Study Completion Date

October 31, 2010

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

Paclitaxel

175 mg/m2 administered on Day 1, of a 21 day cycle. Subjects will receive 2 cycles

DRUG

Carboplatin

Area Under the Curve(AUC)=5 administered on Day 1 of a 21 day cycle. Subjects will receive 2 cycles.

DRUG

CPT-11

100 mg/m2 administered on Day 1 of each 21 day cycle. Subjects will receive 2 cycles.

DRUG

Pegfilgrastim

6 mg administered on Day 2 each each 21 day cylce. Subjects will receive 2 cycles of treatment.

RADIATION

Conformal radiotherapy

Radiation therapy will be administered with standard daily fractionation of 2.0 Gy per fraction, 5 days per week.The total dose of radiotherapy will be 74 Gy

Trial Locations (1)

27599

University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill