14,641
Participants
Start Date
July 31, 1997
Primary Completion Date
June 30, 2011
Study Completion Date
June 30, 2011
Vitamin E
400 IU synthetic alpha-tocopherol or its placebo on alternate days (provided by BASF)
Vitamin C
500 mg synthetic ascorbic acid or its placebo daily (provided by BASF)
Multivitamin
Centrum Silver or its placebo daily (provided by Pfizer (formerly Wyeth, American Home Products, and Lederle))
Beta-carotene
50 mg Lurotin or placebo on alternate days (provided by BASF)
National Cancer Institute (NCI)
NIH
Brigham and Women's Hospital
OTHER