A Study of CNTO 328 in Subjects With Metastatic Renal Cell Carcinoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

August 31, 2003

Primary Completion Date

February 28, 2006

Study Completion Date

February 28, 2006

Conditions
Carcinoma, Renal Cell
Interventions
DRUG

CNTO 328

Patients will receive CNTO 328 at dose levels ranging from 1, 3, 6, and 12 mg/kg in Part 1 of the study to determine the maximum tolerated dose for Part 2 of the study. Patients will receive 2 well tolerated dose levels of CNTO 328 from Part 1 of the study every 3 weeks in Part 2 of the study. Patients will receive 6 mg/kg of CNTO 328 every 2 weeks in Part 3 of the study.

Trial Locations (14)

Unknown

Brno

Hradec nad Svitavou

Caen

Lyon

Montpellier

Montpellier Cedex 5 N/A

Villejuif

Groningen

Nijmegen

Rotterdam

Birmingham

Leeds

Manchester

Plymouth

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Centocor, Inc.

INDUSTRY