14
Participants
Start Date
March 26, 2002
Primary Completion Date
October 10, 2020
Study Completion Date
October 10, 2020
anti-thymocyte globulin
Given 15 mg/kg/day intravenously every 12 hours on Days -5 through -1.
filgrastim
given 5 mcg/kg/day intravenously on Day 1 (continue until absolute neutrophil count (ANC) ≥2.5 x 10\^9/L)
busulfan
Busulfan 0.8 mg/kg intravenously (IV) every 12 hours on Days -7 and -6 (1.0 mg/kg IV if \<4 years old)
cyclophosphamide
10 mg/kg intravenously (IV) on Days -5 through -2.
fludarabine phosphate
35 mg/m\^2 intravenously (IV) on Days -5 through -2.
methylprednisolone
1 mg/kg intravenously (IV) every 12 hours on Days -5 through -1.
Hematopoietic stem cell transplantation
Infused on Day 0 - Donor bone marrow or umbilical cord blood will be collected in the usual sterile manner using established parameters determined by the National Marrow Donor Program.
Masonic Cancer Center, University of Minnesota, Minneapolis
Masonic Cancer Center, University of Minnesota
OTHER