48
Participants
Start Date
April 30, 2004
Primary Completion Date
March 31, 2011
Study Completion Date
July 31, 2012
Doxorubicin
60 mg/m2 IV, bolus once every 14 days x 2-4 cycles
Cyclophosphamide
600 mg/m2 IV once every 14 days x 2-4 cycles
Paclitaxel
80 mg/m2 IV over 1 hour once weekly for 9-12 doses beginning two weeks after completion of last AC dose
Carboplatin
Area under the concentration curve (AUC) 2 IV once weekly for 9-12 doses beginning two weeks after completion of last AC dose
GM-CSF
250 μg/mL IV on day 5-14 of each subcutaneous cycle of doxorubicin and injection cyclophosphamide
Trastuzumab
AUC 2 IV weekly for 12-16 doses beginning two weeks after completion of last AC dose
Chao Family Comprehensive Cancer Center, Orange
Rita Sanghvi, Mehta
OTHER