Trial of Thalidomide, a- Interferon +/- Octreotide in Patients With Unresectable Hepatocellular Carcinoma

PHASE2CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

September 30, 2000

Primary Completion Date

January 31, 2006

Study Completion Date

March 31, 2006

Conditions
LiverCancer
Interventions
DRUG

Thalidomide, alpha interferon

If the patient SSR status is negative, patients will not be given subcutaneous injections of octreotide (Sandostatin LAR) but will receive the thalidomide and alfa interferon only.

DRUG

Thalidomide, interferon, Octreotide

If SSR status is positive or unknown, patients will receive oral doses of thalidomide starting at 200mg a day and increasing to 800mg at increments of 200 per week depending on tolerance. They will also receive injections three times a week of alpha interferon and monthly injections of octreotide (Sandostatin LAR) 30 mg into their buttocks muscle..

Trial Locations (2)

87131

University of New Mexico, Albuquerque

87505

New Mexico Cancer Care Associates, Santa Fe

All Listed Sponsors
lead

University of New Mexico

OTHER

NCT00250796 - Trial of Thalidomide, a- Interferon +/- Octreotide in Patients With Unresectable Hepatocellular Carcinoma | Biotech Hunter | Biotech Hunter