A Study of MLN8054 in Patients With Advanced Solid Tumors

PHASE1TerminatedINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

October 31, 2005

Primary Completion Date

January 31, 2008

Conditions
Breast NeoplasmColon NeoplasmPancreatic NeoplasmBladder Neoplasm
Interventions
DRUG

MLN8054

MLN8054 will be administered orally in multiple divided daily doses for 7 days to 21 consecutive days. A 14-day recovery period will follow each dosing period, regardless of its duration. MLN8054 will be supplied in capsules of 5 mg or 25 mg with dose strength expressed as the milligrams of active drug (free acid). MLN8054 will be given on an empty stomach. Patients will be instructed to take nothing by mouth except for water and prescribed medications for 2 hours before and 1 hour after each dose.

Trial Locations (1)

37203

The Sarah Cannon Research Institute, Nashville

All Listed Sponsors
lead

Millennium Pharmaceuticals, Inc.

INDUSTRY