81
Participants
Start Date
January 31, 2003
Primary Completion Date
May 31, 2006
Study Completion Date
May 31, 2007
Recombinant tissue plasminogen activator
Low-dose IV rt-PA (0.6 mg/kg) followed by delivery of additional IA rt-PA (up to 22 mg).
Low-intensity ultrasound
Delivery of additional IA rt-PA (up to 22 mg) in the setting of low-energy ultrasound via the EKOS microinfusion catheter at the site of IA occlusion in acute ischemic stroke patients with large strokes (NIHSS \>/= 10) treated within 3 hours of symptoms onset.
University of Cincinnati, Cincinnati
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
University of Cincinnati
OTHER