Open Label Study Of SU011248 In Combination With Trastuzumab For Patients With Metastatic Breast Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 28, 2006

Primary Completion Date

April 30, 2009

Study Completion Date

July 31, 2010

Conditions
Breast Neoplasms
Interventions
DRUG

SU011248/Trastuzumab

SU011248 will be administered orally, starting dose of 37.5 mg daily on a continuous regimen. Trastuzumab will be administered weekly (loading dose 4 mg/kg followed by weekly 2mg/kg) or every 3 weeks (loading dose 8 mg/kg followed by 6mg/kg q3w). Study treatment should continue until progression, withdrawal for other reasons, or for up to 18 months following which patients requiring continued access will be offered SU011248 on a separate protocol.

Trial Locations (27)

1340

Pfizer Investigational Site, Ottignies

2610

Pfizer Investigational Site, Wilrijk

10021

Pfizer Investigational Site, New York

19713

Pfizer Investigational Site, Newark

19899

Pfizer Investigational Site, Wilmington

25030

Pfizer Investigational Site, Besançon

28040

Pfizer Investigational Site, Madrid

33308

Pfizer Investigational Site, Fort Lauderdale

36106

Pfizer Investigational Site, Montgomery

38104

Pfizer Investigational Site, Memphis

38120

Pfizer Investigational Site, Memphis

38671

Pfizer Investigational Site, Southaven

38834

Pfizer Investigational Site, Corinth

46010

Pfizer Investigational Site, Valencia

46321

Pfizer Investigational Site, Munster

60426

Pfizer Investigational Site, Harvey

60477

Pfizer Investigational Site, Tinley Park

69373

Pfizer Investigational Site, Lyon

70503

Pfizer Investigational Site, Lafayette

70563

Pfizer Investigational Site, New Iberia

89135

Pfizer Investigational Site, Las Vegas

92210

Pfizer Investigational Site, Saint-Cloud

19718-6001

Pfizer Investigational Site, Newark

M4N 3M5

Pfizer Investigational Site, Toronto

J4V 2H1

Pfizer Investigational Site, Greenfield Park

H3G 1A4

Pfizer Investigational Site, Montreal

08003

Pfizer Investigational Site, Barcelona

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY