141
Participants
Start Date
August 31, 2005
Primary Completion Date
August 31, 2012
Study Completion Date
April 30, 2013
MIS+Cathflo Activase (drug)
MIS+Cathflo Activase (drug): The intervention is a comparison of the safety and preliminary effectiveness of investigational minimally invasive surgery to place a catheter into an intracerebral hemorrhage blood clot and subsequent administration in sequential tiers of 0.3 or 1.0mg of rt-PA, CathFlo® through the catheter once every eight hours for up to 72 hours, in addition to best medical care.
Intraoperative stereotactic CT-Guided Endoscopic Surgery
Mechanical intracerebral hemorrhage removal via an endoscope utilizing the same operative targeting arm as MISTIE arm. No rt-PA administered, and in addition to best medical care.
Mt. Sinai Medical Center, New York
Allegheny General Hospital, Pittsburgh
University of Pittsburgh Medical Center, Pittsburgh
Thomas Jefferson University, Philadelphia
Temple University, Philadelphia
Georgetown University, Washington D.C.
University of Maryland Medical Systems, Baltimore
Johns Hopkins University/Bayview Medical Center, Baltimore
Virginia Commonwealth University, Richmond
Medical University of South Carolina, Charleston
Mayo Clinic, Jacksonville
University of Alabama at Birmingham, Birmingham
Case Western University, Cleveland
University of Cincinnati, Cincinnati
Henry Ford Health System, Detroit
NorthShore University Health System, Evanston
Rush University, Chicago
University of Chicago, Chicago
University of Heidelberg, Heidelberg
University of Texas, Houston, Houston
University of Texas HSC, San Antonio, San Antonio
Barrow Neurosurgical Associates, Phoenix
University of California Los Angeles, Los Angeles
University of California, San Diego, San Diego
Stanford University, Palo Alto
Hartford Hospital, Hartford
JFK Medical Center New Jersey, Edison
Montreal Neurological Institute at McGill University, Montreal
Newcastle General Hospital, Newcastle
Collaborators (2)
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Genentech, Inc.
INDUSTRY
Emissary International LLC
INDUSTRY
Daniel Hanley
OTHER