KL₄Surfactant Treatment in Patients With ARDS

PHASE2TerminatedINTERVENTIONAL
Enrollment

124

Participants

Timeline

Start Date

May 31, 2001

Primary Completion Date

February 28, 2006

Study Completion Date

February 28, 2006

Conditions
Acute Respiratory Distress Syndrome
Interventions
DRUG

A.1 Lucinactant

3 30 mL aliquots at concentrations of 5, 5, and 10 mg/mL

OTHER

B.3 SoC

Standard ARDS management and ICU care

DRUG

A.2 Lucinactant

3 30 mL aliquots at a concentration of 10 mg/mL each

DRUG

A.3 Lucinactant

2 50 mL aliquots at concentrations of 10 and 20 mg/mL

DRUG

A.4 Lucinactant

2 50 mL aliquots at concentrations of 10 and 20 mg/mL, with bolus re-treatment allowed

DRUG

B.1 Lucinactant

2 50 mL aliquots at concentrations of 10 and 20 mg/mL

DRUG

B.2 Lucinactant

2 50 mL aliquots at concentrations of 10 and 20 mg/mL, with bolus re-treatment allowed

Trial Locations (1)

18976-3646

Discovery Laboratories, Inc., Warrington

Sponsors
All Listed Sponsors
lead

Windtree Therapeutics

INDUSTRY