Etanercept and Gemcitabine in Patients With Advanced, Chemotherapy Naive Pancreatic Adenocarcinoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

July 31, 2001

Primary Completion Date

October 31, 2006

Study Completion Date

May 31, 2007

Conditions
Pancreatic NeoplasmsAdenocarcinoma
Interventions
DRUG

Gemcitabine

The starting dose will be 1000mg/m2 IV, weekly x 7 with a one week rest followed by weekly x 3 with one week rest for the remainder of treatment.

DRUG

Etanercept

Etanercept will be self administered subcutaneously by patients with injections 11 prepared by the investigational pharmacy, beginning 7 days prior to the first dose of gemcitabine and continued twice weekly for the duration of the study.

Trial Locations (1)

43210

Ohio State University Medical Center, Columbus

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Immunex Corporation

INDUSTRY

lead

Ohio State University Comprehensive Cancer Center

OTHER